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Dr. José C. Aponte

Photo of JOSÉ APONTE

Dr. José C. Aponte

  • 301.614.6916
  • NASA/GSFC
  • Mail Code: 691
  • Greenbelt , MD 20771
  • Employer: NASA

    • Research Interests

    Extraterrestrial Organic Compounds

    José is an astrochemist in the Astrobiology Analytical Laboratory at NASA’s Goddard Space Flight Center. He works on the development of analytical methods to characterize, quantify, and measure the isotopic and enantiomeric signatures of small organic compounds (e.g. amines, monocarboxylic acids, and amino acids), that are present in carbonaceous chondrites, and that may have been relevant to the origins of life on Earth and possibly elsewhere. José is also a scientific Co-Investigator for the NASA Astrobiology Institute at the Goddard Center for Astrobiology and a Collaborator on the science team for the OSIRIS-REx asteroid sample return mission.

    Education

    Ph.D. in Natural Products and Organic Chemistry (Dec 2009), Chemistry Department, University of Louisville, Kentucky, U.S.A.

    B.S. in Chemistry (Dec 2003), Chemistry Department, Universidad Peruana Cayetano Heredia, Lima, Peru.

    Awards

    • 2022 Robert H. Goddard Honor Exceptional Achievement Award – Science as a member of The Consortium for Hyabusa2 Analysis of Organic Solubles team, NASA Goddard Space Flight Center, June 2022.
    • 2022 Special Thanks And Recognition (STAR) Award, NASA Goddard Space Flight Center, June 2022.
    • 2020 Robert H. Goddard Honor Exceptional Achievement Award - Science, NASA Goddard Space Flight Center, June 2021.
    • Group Achievement Award – OSIRIS-REx Mission team, NASA Goddard Space Flight Center, April 2018.
    • 2017 Asteroid (2005 EY161) discovered at Mount Lemmon on 2005-03-09 by Mt. Lemmon Survey was renamed as Asteroid (117652) Joséaponte, October 2017.
    • 2016 Annual Peer Award, Solar System Exploration Division (Code 690), NASA Goddard Space Flight Center, July 2016.
    • NASA Early Career Fellowship ($100K to be used as laboratory start-up funds after obtaining a tenure-track or equivalent position), Planetary Science Division, NASA ROSES Emerging Worlds solicitation, February 2015.
    • 2014 Student and Early-Career Scientist Travel Grant, given by The International Society for the Study of the Origin of Life – The International Astrobiology Society (ISSOL), to attend the Origins International Conference, Nara, Japan, July 2014.
    • 2012 International Research and Development (IRAD) Innovator of the Year – Team Award, NASA Goddard Space Flight Center, December 2012.
    • 2011 AbGradCon Travel Award to attend the Astrobiology Research Focus Group (RFG) Workshop and the Astrobiology Graduate Conference, June 2011.
    • 2009 Guy Stevenson Award for Excellence in Graduate Studies (the highest honor achievable for a graduate student) given by the School of Interdisciplinary and Graduate Studies, University of Louisville, November 2009.
    • 2009 Graduate Dean’s Citation (an honor given to less than 10% of graduate students) for my significant accomplishments during my graduate studies, University of Louisville, November 2009.
    • MEDI Travel Grant, given by the American Chemical Society, Medicinal Chemistry Division, to attend the American Chemical Society 238th National Meeting & Exposition, June 2009.
    • IMD3 Travel Award, given by the Institute for Molecular Diversity and Drug Design, to attend the American Chemical Society 238th National Meeting & Exposition, May 2009.
    • Lynn Brady Student Travel Award, given by the American Society of Pharmacognosy Foundation to attend the American Society of Pharmacognosy 4th Interim Meeting, April 2008.
    • First Prize in Writing and Second Prize in Painting, Spring Art Contest, Universidad Peruana Cayetano Heredia, October 2002.
    • Second Prize in Writing, Spring Art Contest, Universidad Peruana Cayetano Heredia, October 2001.


    Selected Publications

    Refereed

    Zeichner, S. S., L. Chimiak, J. E. Elsila, et al. A. L. Sessions, J. P. Dworkin, J. C. Aponte, and J. M. Eiler. 2023. "Position-specific carbon isotopes of Murchison amino acids elucidate extraterrestrial abiotic organic synthesis networks." Geochimica et Cosmochimica Acta, 355: 210-221 [Full Text (Link)] [10.1016/j.gca.2023.06.010]

    Hashiguchi, M., D. Aoki, K. Fukushima, et al. H. Naraoka, Y. Takano, J. P. Dworkin, K. E. Dworkin, J. C. Aponte, J. E. Elsila, J. M. Eiler, Y. Furukawa, A. Furusho, D. P. Glavin, H. V. Graham, K. Hamase, N. Hertkorn, J. Isa, T. Koga, H. L. McLain, H. Mita, Y. Oba, N. O. Ogawa, N. Ohkouchi, F.-R. Orthous-Daunay, E. T. Parker, A. Ruf, S. Sakai, P. Schmitt-Kopplin, H. Sugahara, R. Thissen, V. Vuitton, C. Wolters, T. Yoshimura, H. Yurimoto, T. Nakamura, T. Noguchi, R. Okazaki, H. Yabuta, K. Sakamoto, S. Tachibana, T. Yada, M. Nishimura, A. Nakato, A. Miyazaki, K. Yogata, M. Abe, T. Usui, M. Yoshikawa, T. Saiki, S. Tanaka, F. Terui, S. Nakazawa, S.-I. Watanabe, and Y. Tsuda. 2023. "The spatial distribution of soluble organic matter and their relationship to minerals in the asteroid (162173) Ryugu." Earth, Planets and Space, 75 (1): 73 [10.1186/s40623-023-01792-w]

    Aponte, J. C., J. P. Dworkin, D. P. Glavin, et al. J. E. Elsila, E. T. Parker, H. L. McLain, H. Naraoka, R. Okazaki, Y. Takano, S. Tachibana, G. Dong, S. S. Zeichner, J. M. Eiler, H. Yurimoto, T. Nakamura, H. Yabuta, F. Terui, T. Noguchi, K. Sakamoto, T. Yada, M. Nishimura, A. Nakato, A. Miyazaki, K. Yogata, M. Abe, T. Okada, T. Usui, M. Yoshikawa, T. Saiki, S. Tanaka, S. Nakazawa, Y. Tsuda, and S.-I. Watanabe. 2023. "PAHs, hydrocarbons, and dimethylsulfides in Asteroid Ryugu samples A0106 and C0107 and the Orgueil (CI1) meteorite." Earth, Planets and Space, 75 (1): 28 [Full Text (Link)] [10.1186/s40623-022-01758-4]

    Parker, E. T., H. L. McLain, D. P. Glavin, et al. J. P. Dworkin, J. E. Elsila, J. C. Aponte, H. Naraoka, Y. Takano, S. Tachibana, H. Yabuta, H. Yurimoto, K. Sakamoto, T. Yada, M. Nishimura, A. Nakato, A. Miyazaki, K. Yogata, M. Abe, T. Okada, T. Usui, M. Yoshikawa, T. Saiki, S. Tanaka, S. Nakazawa, Y. Tsuda, F. Terui, T. Noguchi, R. Okazaki, S.-I. Watanabe, and T. Nakamura. 2023. "Extraterrestrial Amino Acids and Amines Identified in Asteroid Ryugu Samples Returned by the Hayabusa2 Mission." Geochimica et Cosmochimica Acta, 347: 42-57 [Full Text (Link)] [10.1016/j.gca.2023.02.017]

    Naraoka, H., Y. Takano, J. P. Dworkin, et al. Y. Oba, K. Hamase, A. Furusho, N. O. Ogawa, M. Hashiguchi, K. Fukushima, D. Aoki, P. Schmitt-Kopplin, J. C. Aponte, E. T. Parker, D. P. Glavin, H. L. McLain, J. E. Elsila, H. V. Graham, J. M. Eiler, F.-R. Orthous-Daunay, C.-E. Wolters, J. Isa, V.-E. Vuitton, R. Thissen, S. Sakai, T. Yoshimura, T. Koga, N. Ohkouchi, Y. Chikaraishi, H. Sugahara, H. Mita, Y. Furukawa, N. Hertkorn, A. Ruf, H. Yurimoto, T. Nakamura, T. Noguchi, R. Okazaki, H. Yabuta, K. Sakamoto, S. Tachibana, C. , D. S. Lauretta, M. Abe, T. Yada, M. Nishimura, K. Yogata, A. Nakato, M. Yoshitake, A. Suzuki, A. Miyazaki, S. Furuya, K. Hatakeda, H. Soejima, Y. Hitomi, K. Kumagai, T. Usui, T. Hayashi, D. Yamamoto, R. Fukai, K. Kitazato, S. Sugita, N. Namiki, M. Arakawa, H. Ikeda, M. Ishiguro, N. Hirata, K. Wada, Y. Ishihara, R. Noguchi, T. Morota, N. Sakatani, K. Matsumoto, H. Senshu, R. Honda, E. Tatsumi, Y. Yokota, C. Honda, T. Michikami, M. Matsuoka, A. Miura, H. Noda, T. Yamada, K. Yoshihara, K. Kawahara, M. Ozaki, Y.-I. Iijima, H. Yano, M. Hayakawa, T. Iwata, R. Tsukizaki, H. Sawada, S. Hosoda, K. Ogawa, C. Okamoto, N. Hirata, K. Shirai, Y. Shimaki, M. Yamada, T. Okada, Y. Yamamoto, H. Takeuchi, A. Fujii, Y. Takei, K. Yoshikawa, Y. Mimasu, G. Ono, N. Ogawa, S. Kikuchi, S. Nakazawa, F. Terui, S. Tanaka, T. Saiki, M. Yoshikawa, S.-I. Watanabe, and Y. Tsuda. 2023. "Soluble organic molecules in samples of the carbonaceous asteroid (162173) Ryugu." Science, 379 (6634): eabn9033 [Full Text (Link)] [10.1126/science.abn9033]

    Qasim, D., H. L. McLain, J. C. Aponte, et al. D. P. Glavin, J. P. Dworkin, and C. K. Materese. 2023. "Meteorite Parent Body Aqueous Alteration Simulations of Interstellar Residue Analogs." ACS Earth and Space Chemistry, 7 (1): 156-167 [Full Text (Link)] [10.1021/acsearthspacechem.2c00274]

    Graham, H. V., J. E. Elsila, J. P. Dworkin, S. A. Sandford, and J. C. Aponte. 2022. "Deuterium Isotope Fractionation of Polycyclic Aromatic Hydrocarbons in Meteorites as an Indicator of Interstellar/Protosolar Processing History." Life, 12 (9): 1368 [10.3390/life12091368]

    Giese, C.-C., I. L. ten Kate, M. P. van den Ende, et al. M. Wolthers, J. C. Aponte, E. Camprubi, J. P. Dworkin, J. E. Elsila, S. Hangx, H. E. King, H. L. Mclain, O. Plümper, and A. G. Tielens. 2022. "Experimental and Theoretical Constraints on Amino Acid Formation from PAHs in Asteroidal Settings." ACS Earth and Space Chemistry, 6: 468-481 [Full Text (Link)] [10.1021/acsearthspacechem.1c00329]

    Simkus, D. N., J. C. Aponte, J. E. Elsila, et al. H. L. McLain, E. T. Parker, J. P. Dworkin, and D. P. Glavin. 2021. "Low total abundances and a predominance of n ‐ω‐amino acids in enstatite chondrites: Implications for thermal stability of amino acids in the inner solar system." Meteoritics & Planetary Science, 56 (11): 2118–2127 [Full Text (Link)] [10.1111/maps.13757]

    Koga, T., E. T. Parker, H. L. McLain, et al. J. C. Aponte, J. E. Elsila, J. P. Dworkin, D. P. Glavin, H. Naraoka. 2021. "Extraterrestrial hydroxy amino acids in CM and CR carbonaceous chondrites." Meteoritics & Planetary Science, 56 (6): 1005-1023 [Full Text (Link)] [10.1111/maps.13661]

    Elsila, J. E., N. M. Johnson, D. P. Glavin, J. C. Aponte, and J. P. Dworkin. 2021. "Amino acid abundances and compositions in iron and stony‐iron meteorites." Meteoritics & Planetary Science, 56 (3): 586-600 [Full Text (Link)] [10.1111/maps.13638]

    Chimiak, L., J. Elsila, B. Dallas, et al. J. Dworkin, J. Aponte, A. Sessions, and J. Eiler. 2021. "Carbon isotope evidence for the substrates and mechanisms of prebiotic synthesis in the early solar system." Geochimica et Cosmochimica Acta, 292: 188-202 [Full Text (Link)] [10.1016/j.gca.2020.09.026]

    Aponte, J. C., J. E. Elsila, J. E. Hein, et al. J. P. Dworkin, D. P. Glavin, H. L. Mclain, E. T. Parker, T. Cao, E. L. Berger, and A. S. Burton. 2020. "Analysis of amino acids, hydroxy acids, and amines in CR chondrites." Meteoritics & Planetary Science, 55 (11): 2422-2439 [Full Text (Link)] [10.1111/maps.13586]

    Glavin, D. P., H. L. McLain, J. P. Dworkin, et al. E. T. Parker, J. E. Elsila, J. C. Aponte, D. N. Simkus, C. I. Pozarycki, H. V. Graham, L. R. Nittler, and C. M. Alexander. 2020. "Abundant extraterrestrial amino acids in the primitive CM carbonaceous chondrite Asuka 12236." Meteoritics & Planetary Science, 55 (9): 1979–2006 [Full Text (Link)] [10.1111/maps.13560]

    Vinogradoff, V., L. Remusat, H. L. McLain, et al. J. C. Aponte, S. Bernard, G. Danger, J. P. Dworkin, J. E. Elsila, and M. Jaber. 2020. "Impact of Phyllosilicates on Amino Acid Formation under Asteroidal Conditions." ACS Earth and Space Chemistry, 4 (8): 1398-1407 [Full Text (Link)] [10.1021/acsearthspacechem.0c00137]

    Aponte, J. C., H. L. McLain, D. N. Simkus, et al. J. E. Elsila, D. P. Glavin, E. T. Parker, J. P. Dworkin, D. H. Hill, H. C. Connolly, and D. S. Lauretta. 2020. "Extraterrestrial organic compounds and cyanide in the CM2 carbonaceous chondrites Aguas Zarcas and Murchison." Meteoritics & Planetary Science, 55 (7): 1509-1524 [Full Text (Link)] [10.1111/maps.13531]

    Abreu, N. M., J. C. Aponte, E. A. Cloutis, and L.-A. N. Nguyen. 2020. "The Renazzo-like carbonaceous chondrites as resources to understand the origin, evolution, and exploration of the solar system." Geochemistry, [Full Text (Link)] [10.1016/j.chemer.2020.125631]

    Glavin, D. P., J. E. Elsila, H. L. McLain, et al. J. C. Aponte, E. T. Parker, J. P. Dworkin, D. H. Hill, H. C. Connolly, and D. S. Lauretta. 2020. "Extraterrestrial amino acids and L-enantiomeric excesses in the CM2 carbonaceous chondrites Aguas Zarcas and Murchison." Meteoritics & Planetary Science, 56 (1): 148–173 [Full Text (Link)] [10.1111/maps.13451]

    Glavin, D. P., A. S. Burton, J. E. Elsila, J. C. Aponte, and J. P. Dworkin. 2019. "The Search for Chiral Asymmetry as a Potential Biosignature in our Solar System." Chemical Reviews, 120: 4660−4689 [Full Text (Link)] [10.1021/acs.chemrev.9b00474]

    Simkus, D., J. C. Aponte, J. E. Elsila, et al. E. T. Parker, D. P. Glavin, and J. P. Dworkin. 2019. "Methodologies for Analyzing Soluble Organic Compounds in Extraterrestrial Samples: Amino Acids, Amines, Monocarboxylic Acids, Aldehydes, and Ketones." Life, 9 (47): 30 pages [Full Text (Link)] [10.3390/life9020047]

    Simkus, D. N., J. C. Aponte, J. E. Elsila, et al. R. W. Hilts, H. L. McLain, and C. D. Herd. 2019. "New insights into the heterogeneity of the Tagish Lake meteorite: Soluble organic compositions of variously altered specimens." Meteoritics & Planetary Science, 54: 1283-1302 [10.1111/maps.13276]

    Aponte, J. C., D. Whitaker, M. W. Powner, J. E. Cook, and J. P. Dworkin. 2019. "Analyses of Aliphatic Aldehydes and Ketones in Carbonaceous Chondrites." ACS Earth & Space Chemistry, 3: 463-472 [Full Text (Link)] [10.1021/acsearthspacechem.9b00006]

    Aponte, J. C., H. K. Woodward, N. M. Abreu, J. E. Elsila, and J. P. Dworkin. 2019. "Molecular distribution, 13C-isotope, and enantiomeric compositions of carbonaceous chondrite monocarboxylic acids." Meteoritics & Planetary Science, 54 (2): 415-430 [Full Text (Link)] [10.1111/maps.13216]

    Simkus, D. N., J. C. Aponte, R. W. Hilts, J. E. Elsila, and C. D. Herd. 2019. "Compound-specific carbon isotope compositions of aldehydes and ketones in the Murchison meteorite." Meteoritics & Planetary Science, 54 (1): 142-156 [10.1111/maps.13202]

    Dworkin, J. P., L. A. Adelman, T. Ajluni, et al. A. V. Andronikov, J. C. Aponte, A. E. Bartels, E. Beshore, E. B. Bierhaus, J. R. Brucato, B. H. Bryan, A. S. Burton, M. P. Callahan, S. L. Castro-Wallace, B. C. Clark, S. J. Clemett, H. C. Connolly, W. E. Cutlip, S. M. Daly, V. E. Elliott, J. E. Elsila, H. L. Enos, D. F. Everett, I. A. Franchi, D. P. Glavin, H. V. Graham, J. E. Hendershot, J. W. Harris, S. L. Hill, A. R. Hildebrand, G. O. Jayne, R. W. Jenkens, K. S. Johnson, J. S. Kirsch, D. S. Lauretta, A. S. Lewis, J. J. Loiacono, C. C. Lorentson, J. R. Marshall, M. G. Martin, L. L. Matthias, H. L. McLain, S. R. Messenger, R. G. Mink, J. L. Moore, K. Nakamura-Messenger, J. A. Nuth, C. V. Owens, C. L. Parish, B. D. Perkins, M. S. Pryzby, C. A. Reigle, K. Righter, B. Rizk, J. F. Russell, S. A. Sandford, J. P. Schepis, J. Songer, M. F. Sovinski, S. E. Stahl, K. Thomas-Keprta, J. M. Vellinga, and M. S. Walker. 2018. "OSIRIS-REx Contamination Control Strategy and Implementation." Space Science Reviews, 214 (1): 19 [Full Text (Link)] [10.1007/s11214-017-0439-4]

    Glavin, D. P., C. M. Alexander, J. C. Aponte, et al. J. P. Dworkin, J. E. Elsila, and H. Yabuta. 2018. "The Origin and Evolution of Organic Matter in Carbonaceous Chondrites and Links to Their Parent Bodies." Primitive Meteorites and Asteroids, Amsterdam, Netherlands: 205-271, ISBN: 978-0-12-813325-5. [Full Text (Link)] [10.1016/b978-0-12-813325-5.00003-3]

    Pietrucci, F., J. C. Aponte, R. D. Starr, et al. A. Pérez-Villa, J. E. Cook, J. P. Dworkin, and M. Saitta. 2018. "Hydrothermal Decomposition of Amino Acids and Origins of Prebiotic Meteoritic Organic Compounds." ACS Earth & Space Chemistry, 2 (6): 588-598 [Full Text (Link)] [10.1021/acsearthspacechem.8b00025]

    Aponte, J. C., N. M. Abreu, D. P. Glavin, J. P. Dworkin, and J. E. Elsila. 2017. "Distribution of aliphatic amines in CO, CV, and CK carbonaceous chondrites and relation to mineralogy and processing history." Meteoritics & Planetary Science, 52 (12): 2632–2646 [Full Text (Link)] [10.1111/maps.12959]

    Aponte, J. C., J. E. Elsila, D. P. Glavin, et al. S. N. Milam, S. B. Charnley, and J. P. Dworkin. 2017. "Pathways to Meteoritic Glycine and Methylamine." ACS Earth and Space Chemistry, 1 (1): 3-13 [Full Text (Link)] [10.1021/acsearthspacechem.6b00014]

    Elsila, J. E., J. C. Aponte, D. G. Blackmond, et al. A. S. Burton, J. P. Dworkin, and D. P. Glavin. 2016. "Meteoritic Amino Acids: Diversity in Compositions Reflects Parent Body Histories." ACS Central Science, 2: 370-379 [Full Text (Link)] [10.1021/acscentsci.6b00074]

    Aponte, J. C., H. L. McLain, J. P. Dworkin, and J. E. Elsila. 2016. "Aliphatic Amines in Antarctic CR2, CM2, and CM1/2 Carbonaceous Chondrites." Geochimica et Cosmochimica Acta, 189: 296-311 [Full Text (Link)] [10.1016/j.gca.2016.06.018]

    Huang, Y., J. C. Aponte, J. Zhao, R. Tarozo, and C. Hallmann. 2015. "Hydrogen and carbon isotopic ratios of polycyclic aromatic compounds in two CM2 carbonaceous chondrites and implications for prebiotic organic synthesis." Earth and Planetary Science Letters, 426: 101-108 [Full Text (Link)] [10.1016/j.epsl.2015.06.027]

    Aponte, J. C., J. P. Dworkin, and J. E. Elsila. 2015. "Indigenous aliphatic amines in the aqueously altered Orgueil meteorite." Meteoritics & Planetary Science, 50: 1733-1749 [Full Text (Link)] [10.1111/maps.12507]

    Aponte, J. C., J. P. Dworkin, and J. E. Elsila. 2014. "Assessing the origins of aliphatic amines in the Murchison meteorite from their compound-specific carbon isotopic ratios and enantiomeric composition." Geochimica et Cosmochimica Acta, 141: 331-345 [Full Text (Link)] [10.1016/j.gca.2014.06.035 ]

    Aponte, J. C., R. Tarozo, M. R. Alexandre, et al. C. M. Alexander, S. B. Charnley, C. Hallmann, R. E. Summons, and Y. Huang. 2014. "Chirality of meteoritic free and IOM-derived monocarboxylic acids and implications for prebiotic organic synthesis." Geochimica et Cosmochimica Acta, 131: 1-12 [Full Text (Link)] [10.1016/j.gca.2014.01.035]

    Dillon, J. T., J. C. Aponte, R. Tarozo, and Y. Huang. 2013. "Purification of Omega-3 Polyunsaturated Fatty Acids From Fish Oil Using Silver-Thiolate Chromatographic Material and High Performance Liquid Chromatography." Journal of Chromatography A, 1312: 18-25 [Full Text (Link)]

    Aponte, J. C., J. T. Dillon, and Y. Huang. 2013. "The Unique Liquid Chromatographic Properties of Group 11 Transition Metal for the Separation of Unsaturated Organic Compounds." Journal of Separation Science, 36: 2563-2570 [Full Text (Link)]

    Aponte, J. C., J. T. Dillon, R. Tarozo, and Y. Huang. 2012. "Separation of Unsaturated Organic Compounds Using Silver-Thiolate Chromatographic Material." Journal of Chromatography A, 1240: 83-89 [Full Text (Link)] [10.1016/j.chroma.2012.03.082]

    Dillon, J. T., J. C. Aponte, R. Tarozo, and Y. Huang. 2012. "Efficient HPLC Analysis of Mono-, Di-, and Triglycerides Using Silver-Thiolate Chromatographic Material." Journal of Chromatography A, 1240: 90-95 [Full Text (Link)]

    Dillon, J. T., J. C. Aponte, Y.-J. Tsai, and Y. Huang. 2012. "Thin Layer Chromatography in the Separation of Unsaturated Organic Compounds Using Silver-Thiolate Chromatographic Material." Journal of Chromatography A, 1251: 240-243 [Full Text (Link)]

    Aponte, J. C., Z. Jin, A. J. Vaisberg, et al. D. Castillo, E. Malaga, W. H. Lewis, M. Sauvain, R. H. Gilman, and G. B. Hammond. 2011. "Cytotoxic and Antiinfective Phenolic Compounds Isolated from Mikania decora (Compositae) and Cremastosperma microcarpum (Annonaceae)." Planta Medica, 77: 1597-1599 [Full Text (Link)]

    Aponte, J. C., M. R. Alexandre, Y. Wang, et al. A. J. Brearley, C. Alexander, and Y. Huang. 2011. "Effects of Secondary Alteration on the Composition of Free and IOM-Derived Monocarboxylic Acids in Carbonaceous Chondrites." Geochimica et Cosmochimica Acta, 75: 2309-2323 [Full Text (Link)] [10.1016/j.gca.2011.01.040]

    Aponte, J. C., H. Yang, A. J. Vaisberg, et al. D. Castillo, M. Verastegui, E. Malaga, R. H. Gilman, R. Rojas, I. Fernandez, W. H. Lewis, M. Sauvain, and G. B. Hammond. 2010. "Cytotoxic and Anti-infective Compounds Present in Plagiochila disticha (Plagiochilaceae) and Ambrosia peruviana (Asteraceae)." Planta Medica, 76: 705-707 [Full Text (Link)]

    Aponte, J. C., D. Castillo, Y. Estevez, et al. G. Gonzalez, J. Arevalo, G. B. Hammond, and M. Sauvain. 2010. "In Vitro and In Vivo Anti-Leishmania Activity of Polysubstituted Synthetic Chalcones." Bioorganic and Medicinal Chemistry Letters, 20: 100-103 [Full Text (Link)]

    Aponte, J. C., A. J. Vaisberg, D. Castillo, et al. G. Gonzalez, J. Arevalo, M. Sauvain, M. Verastegui, E. Malaga, M. Quiliano, M. Zimic, R. H. Gilman, Y. Wang, S. Franzblau, G. Pauli, and G. B. Hammond. 2010. "Trypanoside, Anti-Tuberculosis, Leishmanicidal and Cytotoxic Activities of Tetrahydrobenzothienopyrimidines." Bioorganic and Medicinal Chemistry, 18: 2880-2886 [Full Text (Link)]

    Aponte, J. C., A. J. Vaisberg, R. Rojas, et al. M. Sauvain, W. H. Lewis, G. Lamas, C. Sarasara, R. H. Gilman, and G. B. Hammond. 2009. "A Multipronged Approach to the Study of Peruvian Ethnomedicinal Plants: A Legacy of the ICBG-Peru Project." Journal of Natural Products, 72: 524-526 [Full Text (Link)]

    Aponte, J. C., G. B. Hammond, and B. Xu. 2009. "TBAF-Mediated Aldol Reaction of b-Allenoates: Regio- and Stereoselective Synthesis of (2E, 4E)-4-Carbinol Alkadienoates." Journal of Organic Chemistry, 74: 4623-4625 [Full Text (Link)]

    Aponte, J. C., A. J. Vaisberg, R. Rojas, et al. L. Caviedes, W. L. Lewis, G. Lamas, C. Sarasara, and R. H. Gilman. 2008. "Isolation of Cytotoxic Metabolites from Targeted Peruvian Amazonian Medicinal Plants." Journal of Natural Products, 71: 102-105 [Full Text (Link)]

    Aponte, J. C., Y. Estevez, R. H. Gilman, et al. W. H. Lewis, R. Rojas, M. Sauvain, A. J. Vaisberg, and G. B. Hammond. 2008. "Antiinfective and Cytotoxic Compounds Present in Blepharodon nitidum (Asclepiadaceae)." Planta Medica, 74: 407-410 [Full Text (Link)]

    Aponte, J. C., M. Verastegui, E. Malaga, et al. M. Zimic, M. Quiliano, A. J. Vaisberg, R. H. Gilman, and G. B. Hammond. 2008. "Synthesis, Cytotoxicity, and Anti-Trypanosoma cruzi Activity of New Chalcones." Journal of Medicinal Chemistry, 51: 6230-6234 [Full Text (Link)]

    Rojas, R., L. Caviedes, J. C. Aponte, et al. A. J. Vaisberg, W. H. Lewis, G. Lamas, C. Sarasara, R. H. Gilman, and G. B. Hammond. 2006. "Aegicerin, the First Oleanane Triterpene with Wide-Ranging Antimycobacterial Activity, Isolated from Clavija procera." Journal of Natural Products, 69: 845-846 [Full Text (Link)]

    Professional Societies

    American Chemical Society , 2006 - Present
    The Meteoritical Society, 2010 - Present

    Selected Public Outreach

    NASA Explorers | Season Five: Artemis Generation 9 / 2022 - 10 / 2022
    https://svs.gsfc.nasa.gov/14205

    Selected Publications

    Refereed

    Zeichner, S. S., L. Chimiak, J. E. Elsila, et al. A. L. Sessions, J. P. Dworkin, J. C. Aponte, and J. M. Eiler. 2023. "Position-specific carbon isotopes of Murchison amino acids elucidate extraterrestrial abiotic organic synthesis networks." Geochimica et Cosmochimica Acta 355 210-221 [Full Text (Link)] [10.1016/j.gca.2023.06.010]

    Hashiguchi, M., D. Aoki, K. Fukushima, et al. H. Naraoka, Y. Takano, J. P. Dworkin, K. E. Dworkin, J. C. Aponte, J. E. Elsila, J. M. Eiler, Y. Furukawa, A. Furusho, D. P. Glavin, H. V. Graham, K. Hamase, N. Hertkorn, J. Isa, T. Koga, H. L. McLain, H. Mita, Y. Oba, N. O. Ogawa, N. Ohkouchi, F.-R. Orthous-Daunay, E. T. Parker, A. Ruf, S. Sakai, P. Schmitt-Kopplin, H. Sugahara, R. Thissen, V. Vuitton, C. Wolters, T. Yoshimura, H. Yurimoto, T. Nakamura, T. Noguchi, R. Okazaki, H. Yabuta, K. Sakamoto, S. Tachibana, T. Yada, M. Nishimura, A. Nakato, A. Miyazaki, K. Yogata, M. Abe, T. Usui, M. Yoshikawa, T. Saiki, S. Tanaka, F. Terui, S. Nakazawa, S.-I. Watanabe, and Y. Tsuda. 2023. "The spatial distribution of soluble organic matter and their relationship to minerals in the asteroid (162173) Ryugu." Earth, Planets and Space 75 (1): 73 [10.1186/s40623-023-01792-w]

    Aponte, J. C., J. P. Dworkin, D. P. Glavin, et al. J. E. Elsila, E. T. Parker, H. L. McLain, H. Naraoka, R. Okazaki, Y. Takano, S. Tachibana, G. Dong, S. S. Zeichner, J. M. Eiler, H. Yurimoto, T. Nakamura, H. Yabuta, F. Terui, T. Noguchi, K. Sakamoto, T. Yada, M. Nishimura, A. Nakato, A. Miyazaki, K. Yogata, M. Abe, T. Okada, T. Usui, M. Yoshikawa, T. Saiki, S. Tanaka, S. Nakazawa, Y. Tsuda, and S.-I. Watanabe. 2023. "PAHs, hydrocarbons, and dimethylsulfides in Asteroid Ryugu samples A0106 and C0107 and the Orgueil (CI1) meteorite." Earth, Planets and Space 75 (1): 28 [Full Text (Link)] [10.1186/s40623-022-01758-4]

    Parker, E. T., H. L. McLain, D. P. Glavin, et al. J. P. Dworkin, J. E. Elsila, J. C. Aponte, H. Naraoka, Y. Takano, S. Tachibana, H. Yabuta, H. Yurimoto, K. Sakamoto, T. Yada, M. Nishimura, A. Nakato, A. Miyazaki, K. Yogata, M. Abe, T. Okada, T. Usui, M. Yoshikawa, T. Saiki, S. Tanaka, S. Nakazawa, Y. Tsuda, F. Terui, T. Noguchi, R. Okazaki, S.-I. Watanabe, and T. Nakamura. 2023. "Extraterrestrial Amino Acids and Amines Identified in Asteroid Ryugu Samples Returned by the Hayabusa2 Mission." Geochimica et Cosmochimica Acta 347 42-57 [Full Text (Link)] [10.1016/j.gca.2023.02.017]

    Naraoka, H., Y. Takano, J. P. Dworkin, et al. Y. Oba, K. Hamase, A. Furusho, N. O. Ogawa, M. Hashiguchi, K. Fukushima, D. Aoki, P. Schmitt-Kopplin, J. C. Aponte, E. T. Parker, D. P. Glavin, H. L. McLain, J. E. Elsila, H. V. Graham, J. M. Eiler, F.-R. Orthous-Daunay, C.-E. Wolters, J. Isa, V.-E. Vuitton, R. Thissen, S. Sakai, T. Yoshimura, T. Koga, N. Ohkouchi, Y. Chikaraishi, H. Sugahara, H. Mita, Y. Furukawa, N. Hertkorn, A. Ruf, H. Yurimoto, T. Nakamura, T. Noguchi, R. Okazaki, H. Yabuta, K. Sakamoto, S. Tachibana, C. , D. S. Lauretta, M. Abe, T. Yada, M. Nishimura, K. Yogata, A. Nakato, M. Yoshitake, A. Suzuki, A. Miyazaki, S. Furuya, K. Hatakeda, H. Soejima, Y. Hitomi, K. Kumagai, T. Usui, T. Hayashi, D. Yamamoto, R. Fukai, K. Kitazato, S. Sugita, N. Namiki, M. Arakawa, H. Ikeda, M. Ishiguro, N. Hirata, K. Wada, Y. Ishihara, R. Noguchi, T. Morota, N. Sakatani, K. Matsumoto, H. Senshu, R. Honda, E. Tatsumi, Y. Yokota, C. Honda, T. Michikami, M. Matsuoka, A. Miura, H. Noda, T. Yamada, K. Yoshihara, K. Kawahara, M. Ozaki, Y.-I. Iijima, H. Yano, M. Hayakawa, T. Iwata, R. Tsukizaki, H. Sawada, S. Hosoda, K. Ogawa, C. Okamoto, N. Hirata, K. Shirai, Y. Shimaki, M. Yamada, T. Okada, Y. Yamamoto, H. Takeuchi, A. Fujii, Y. Takei, K. Yoshikawa, Y. Mimasu, G. Ono, N. Ogawa, S. Kikuchi, S. Nakazawa, F. Terui, S. Tanaka, T. Saiki, M. Yoshikawa, S.-I. Watanabe, and Y. Tsuda. 2023. "Soluble organic molecules in samples of the carbonaceous asteroid (162173) Ryugu." Science 379 (6634): eabn9033 [Full Text (Link)] [10.1126/science.abn9033]

    Qasim, D., H. L. McLain, J. C. Aponte, et al. D. P. Glavin, J. P. Dworkin, and C. K. Materese. 2023. "Meteorite Parent Body Aqueous Alteration Simulations of Interstellar Residue Analogs." ACS Earth and Space Chemistry 7 (1): 156-167 [Full Text (Link)] [10.1021/acsearthspacechem.2c00274]

    Graham, H. V., J. E. Elsila, J. P. Dworkin, S. A. Sandford, and J. C. Aponte. 2022. "Deuterium Isotope Fractionation of Polycyclic Aromatic Hydrocarbons in Meteorites as an Indicator of Interstellar/Protosolar Processing History." Life 12 (9): 1368 [10.3390/life12091368]

    Giese, C.-C., I. L. ten Kate, M. P. van den Ende, et al. M. Wolthers, J. C. Aponte, E. Camprubi, J. P. Dworkin, J. E. Elsila, S. Hangx, H. E. King, H. L. Mclain, O. Plümper, and A. G. Tielens. 2022. "Experimental and Theoretical Constraints on Amino Acid Formation from PAHs in Asteroidal Settings." ACS Earth and Space Chemistry 6 468-481 [Full Text (Link)] [10.1021/acsearthspacechem.1c00329]

    Simkus, D. N., J. C. Aponte, J. E. Elsila, et al. H. L. McLain, E. T. Parker, J. P. Dworkin, and D. P. Glavin. 2021. "Low total abundances and a predominance of n ‐ω‐amino acids in enstatite chondrites: Implications for thermal stability of amino acids in the inner solar system." Meteoritics & Planetary Science 56 (11): 2118–2127 [Full Text (Link)] [10.1111/maps.13757]

    Koga, T., E. T. Parker, H. L. McLain, et al. J. C. Aponte, J. E. Elsila, J. P. Dworkin, D. P. Glavin, H. Naraoka. 2021. "Extraterrestrial hydroxy amino acids in CM and CR carbonaceous chondrites." Meteoritics & Planetary Science 56 (6): 1005-1023 [Full Text (Link)] [10.1111/maps.13661]

    Elsila, J. E., N. M. Johnson, D. P. Glavin, J. C. Aponte, and J. P. Dworkin. 2021. "Amino acid abundances and compositions in iron and stony‐iron meteorites." Meteoritics & Planetary Science 56 (3): 586-600 [Full Text (Link)] [10.1111/maps.13638]

    Chimiak, L., J. Elsila, B. Dallas, et al. J. Dworkin, J. Aponte, A. Sessions, and J. Eiler. 2021. "Carbon isotope evidence for the substrates and mechanisms of prebiotic synthesis in the early solar system." Geochimica et Cosmochimica Acta 292 188-202 [Full Text (Link)] [10.1016/j.gca.2020.09.026]

    Aponte, J. C., J. E. Elsila, J. E. Hein, et al. J. P. Dworkin, D. P. Glavin, H. L. Mclain, E. T. Parker, T. Cao, E. L. Berger, and A. S. Burton. 2020. "Analysis of amino acids, hydroxy acids, and amines in CR chondrites." Meteoritics & Planetary Science 55 (11): 2422-2439 [Full Text (Link)] [10.1111/maps.13586]

    Glavin, D. P., H. L. McLain, J. P. Dworkin, et al. E. T. Parker, J. E. Elsila, J. C. Aponte, D. N. Simkus, C. I. Pozarycki, H. V. Graham, L. R. Nittler, and C. M. Alexander. 2020. "Abundant extraterrestrial amino acids in the primitive CM carbonaceous chondrite Asuka 12236." Meteoritics & Planetary Science 55 (9): 1979–2006 [Full Text (Link)] [10.1111/maps.13560]

    Vinogradoff, V., L. Remusat, H. L. McLain, et al. J. C. Aponte, S. Bernard, G. Danger, J. P. Dworkin, J. E. Elsila, and M. Jaber. 2020. "Impact of Phyllosilicates on Amino Acid Formation under Asteroidal Conditions." ACS Earth and Space Chemistry 4 (8): 1398-1407 [Full Text (Link)] [10.1021/acsearthspacechem.0c00137]

    Aponte, J. C., H. L. McLain, D. N. Simkus, et al. J. E. Elsila, D. P. Glavin, E. T. Parker, J. P. Dworkin, D. H. Hill, H. C. Connolly, and D. S. Lauretta. 2020. "Extraterrestrial organic compounds and cyanide in the CM2 carbonaceous chondrites Aguas Zarcas and Murchison." Meteoritics & Planetary Science 55 (7): 1509-1524 [Full Text (Link)] [10.1111/maps.13531]

    Abreu, N. M., J. C. Aponte, E. A. Cloutis, and L.-A. N. Nguyen. 2020. "The Renazzo-like carbonaceous chondrites as resources to understand the origin, evolution, and exploration of the solar system." Geochemistry [Full Text (Link)] [10.1016/j.chemer.2020.125631]

    Glavin, D. P., J. E. Elsila, H. L. McLain, et al. J. C. Aponte, E. T. Parker, J. P. Dworkin, D. H. Hill, H. C. Connolly, and D. S. Lauretta. 2020. "Extraterrestrial amino acids and L-enantiomeric excesses in the CM2 carbonaceous chondrites Aguas Zarcas and Murchison." Meteoritics & Planetary Science 56 (1): 148–173 [Full Text (Link)] [10.1111/maps.13451]

    Glavin, D. P., A. S. Burton, J. E. Elsila, J. C. Aponte, and J. P. Dworkin. 2019. "The Search for Chiral Asymmetry as a Potential Biosignature in our Solar System." Chemical Reviews 120 4660−4689 [Full Text (Link)] [10.1021/acs.chemrev.9b00474]

    Simkus, D., J. C. Aponte, J. E. Elsila, et al. E. T. Parker, D. P. Glavin, and J. P. Dworkin. 2019. "Methodologies for Analyzing Soluble Organic Compounds in Extraterrestrial Samples: Amino Acids, Amines, Monocarboxylic Acids, Aldehydes, and Ketones." Life 9 (47): 30 pages [Full Text (Link)] [10.3390/life9020047]

    Simkus, D. N., J. C. Aponte, J. E. Elsila, et al. R. W. Hilts, H. L. McLain, and C. D. Herd. 2019. "New insights into the heterogeneity of the Tagish Lake meteorite: Soluble organic compositions of variously altered specimens." Meteoritics & Planetary Science 54 1283-1302 [10.1111/maps.13276]

    Aponte, J. C., D. Whitaker, M. W. Powner, J. E. Cook, and J. P. Dworkin. 2019. "Analyses of Aliphatic Aldehydes and Ketones in Carbonaceous Chondrites." ACS Earth & Space Chemistry 3 463-472 [Full Text (Link)] [10.1021/acsearthspacechem.9b00006]

    Aponte, J. C., H. K. Woodward, N. M. Abreu, J. E. Elsila, and J. P. Dworkin. 2019. "Molecular distribution, 13C-isotope, and enantiomeric compositions of carbonaceous chondrite monocarboxylic acids." Meteoritics & Planetary Science 54 (2): 415-430 [Full Text (Link)] [10.1111/maps.13216]

    Simkus, D. N., J. C. Aponte, R. W. Hilts, J. E. Elsila, and C. D. Herd. 2019. "Compound-specific carbon isotope compositions of aldehydes and ketones in the Murchison meteorite." Meteoritics & Planetary Science 54 (1): 142-156 [10.1111/maps.13202]

    Dworkin, J. P., L. A. Adelman, T. Ajluni, et al. A. V. Andronikov, J. C. Aponte, A. E. Bartels, E. Beshore, E. B. Bierhaus, J. R. Brucato, B. H. Bryan, A. S. Burton, M. P. Callahan, S. L. Castro-Wallace, B. C. Clark, S. J. Clemett, H. C. Connolly, W. E. Cutlip, S. M. Daly, V. E. Elliott, J. E. Elsila, H. L. Enos, D. F. Everett, I. A. Franchi, D. P. Glavin, H. V. Graham, J. E. Hendershot, J. W. Harris, S. L. Hill, A. R. Hildebrand, G. O. Jayne, R. W. Jenkens, K. S. Johnson, J. S. Kirsch, D. S. Lauretta, A. S. Lewis, J. J. Loiacono, C. C. Lorentson, J. R. Marshall, M. G. Martin, L. L. Matthias, H. L. McLain, S. R. Messenger, R. G. Mink, J. L. Moore, K. Nakamura-Messenger, J. A. Nuth, C. V. Owens, C. L. Parish, B. D. Perkins, M. S. Pryzby, C. A. Reigle, K. Righter, B. Rizk, J. F. Russell, S. A. Sandford, J. P. Schepis, J. Songer, M. F. Sovinski, S. E. Stahl, K. Thomas-Keprta, J. M. Vellinga, and M. S. Walker. 2018. "OSIRIS-REx Contamination Control Strategy and Implementation." Space Science Reviews 214 (1): 19 [Full Text (Link)] [10.1007/s11214-017-0439-4]

    Glavin, D. P., C. M. Alexander, J. C. Aponte, et al. J. P. Dworkin, J. E. Elsila, and H. Yabuta. 2018. "The Origin and Evolution of Organic Matter in Carbonaceous Chondrites and Links to Their Parent Bodies." Primitive Meteorites and Asteroids 205-271 [Full Text (Link)] [10.1016/b978-0-12-813325-5.00003-3]

    Pietrucci, F., J. C. Aponte, R. D. Starr, et al. A. Pérez-Villa, J. E. Cook, J. P. Dworkin, and M. Saitta. 2018. "Hydrothermal Decomposition of Amino Acids and Origins of Prebiotic Meteoritic Organic Compounds." ACS Earth & Space Chemistry 2 (6): 588-598 [Full Text (Link)] [10.1021/acsearthspacechem.8b00025]

    Aponte, J. C., N. M. Abreu, D. P. Glavin, J. P. Dworkin, and J. E. Elsila. 2017. "Distribution of aliphatic amines in CO, CV, and CK carbonaceous chondrites and relation to mineralogy and processing history." Meteoritics & Planetary Science 52 (12): 2632–2646 [Full Text (Link)] [10.1111/maps.12959]

    Aponte, J. C., J. E. Elsila, D. P. Glavin, et al. S. N. Milam, S. B. Charnley, and J. P. Dworkin. 2017. "Pathways to Meteoritic Glycine and Methylamine." ACS Earth and Space Chemistry 1 (1): 3-13 [Full Text (Link)] [10.1021/acsearthspacechem.6b00014]

    Elsila, J. E., J. C. Aponte, D. G. Blackmond, et al. A. S. Burton, J. P. Dworkin, and D. P. Glavin. 2016. "Meteoritic Amino Acids: Diversity in Compositions Reflects Parent Body Histories." ACS Central Science 2 370-379 [Full Text (Link)] [10.1021/acscentsci.6b00074]

    Aponte, J. C., H. L. McLain, J. P. Dworkin, and J. E. Elsila. 2016. "Aliphatic Amines in Antarctic CR2, CM2, and CM1/2 Carbonaceous Chondrites." Geochimica et Cosmochimica Acta 189 296-311 [Full Text (Link)] [10.1016/j.gca.2016.06.018]

    Huang, Y., J. C. Aponte, J. Zhao, R. Tarozo, and C. Hallmann. 2015. "Hydrogen and carbon isotopic ratios of polycyclic aromatic compounds in two CM2 carbonaceous chondrites and implications for prebiotic organic synthesis." Earth and Planetary Science Letters 426 101-108 [Full Text (Link)] [10.1016/j.epsl.2015.06.027]

    Aponte, J. C., J. P. Dworkin, and J. E. Elsila. 2015. "Indigenous aliphatic amines in the aqueously altered Orgueil meteorite." Meteoritics & Planetary Science 50 1733-1749 [Full Text (Link)] [10.1111/maps.12507]

    Aponte, J. C., J. P. Dworkin, and J. E. Elsila. 2014. "Assessing the origins of aliphatic amines in the Murchison meteorite from their compound-specific carbon isotopic ratios and enantiomeric composition." Geochimica et Cosmochimica Acta 141 331-345 [Full Text (Link)] [10.1016/j.gca.2014.06.035 ]

    Aponte, J. C., R. Tarozo, M. R. Alexandre, et al. C. M. Alexander, S. B. Charnley, C. Hallmann, R. E. Summons, and Y. Huang. 2014. "Chirality of meteoritic free and IOM-derived monocarboxylic acids and implications for prebiotic organic synthesis." Geochimica et Cosmochimica Acta 131 1-12 [Full Text (Link)] [10.1016/j.gca.2014.01.035]

    Dillon, J. T., J. C. Aponte, R. Tarozo, and Y. Huang. 2013. "Purification of Omega-3 Polyunsaturated Fatty Acids From Fish Oil Using Silver-Thiolate Chromatographic Material and High Performance Liquid Chromatography." Journal of Chromatography A 1312 18-25 [Full Text (Link)]

    Aponte, J. C., J. T. Dillon, and Y. Huang. 2013. "The Unique Liquid Chromatographic Properties of Group 11 Transition Metal for the Separation of Unsaturated Organic Compounds." Journal of Separation Science 36 2563-2570 [Full Text (Link)]

    Aponte, J. C., J. T. Dillon, R. Tarozo, and Y. Huang. 2012. "Separation of Unsaturated Organic Compounds Using Silver-Thiolate Chromatographic Material." Journal of Chromatography A 1240 83-89 [Full Text (Link)] [10.1016/j.chroma.2012.03.082]

    Dillon, J. T., J. C. Aponte, R. Tarozo, and Y. Huang. 2012. "Efficient HPLC Analysis of Mono-, Di-, and Triglycerides Using Silver-Thiolate Chromatographic Material." Journal of Chromatography A 1240 90-95 [Full Text (Link)]

    Dillon, J. T., J. C. Aponte, Y.-J. Tsai, and Y. Huang. 2012. "Thin Layer Chromatography in the Separation of Unsaturated Organic Compounds Using Silver-Thiolate Chromatographic Material." Journal of Chromatography A 1251 240-243 [Full Text (Link)]

    Aponte, J. C., Z. Jin, A. J. Vaisberg, et al. D. Castillo, E. Malaga, W. H. Lewis, M. Sauvain, R. H. Gilman, and G. B. Hammond. 2011. "Cytotoxic and Antiinfective Phenolic Compounds Isolated from Mikania decora (Compositae) and Cremastosperma microcarpum (Annonaceae)." Planta Medica 77 1597-1599 [Full Text (Link)]

    Aponte, J. C., M. R. Alexandre, Y. Wang, et al. A. J. Brearley, C. Alexander, and Y. Huang. 2011. "Effects of Secondary Alteration on the Composition of Free and IOM-Derived Monocarboxylic Acids in Carbonaceous Chondrites." Geochimica et Cosmochimica Acta 75 2309-2323 [Full Text (Link)] [10.1016/j.gca.2011.01.040]

    Aponte, J. C., H. Yang, A. J. Vaisberg, et al. D. Castillo, M. Verastegui, E. Malaga, R. H. Gilman, R. Rojas, I. Fernandez, W. H. Lewis, M. Sauvain, and G. B. Hammond. 2010. "Cytotoxic and Anti-infective Compounds Present in Plagiochila disticha (Plagiochilaceae) and Ambrosia peruviana (Asteraceae)." Planta Medica 76 705-707 [Full Text (Link)]

    Aponte, J. C., D. Castillo, Y. Estevez, et al. G. Gonzalez, J. Arevalo, G. B. Hammond, and M. Sauvain. 2010. "In Vitro and In Vivo Anti-Leishmania Activity of Polysubstituted Synthetic Chalcones." Bioorganic and Medicinal Chemistry Letters 20 100-103 [Full Text (Link)]

    Aponte, J. C., A. J. Vaisberg, D. Castillo, et al. G. Gonzalez, J. Arevalo, M. Sauvain, M. Verastegui, E. Malaga, M. Quiliano, M. Zimic, R. H. Gilman, Y. Wang, S. Franzblau, G. Pauli, and G. B. Hammond. 2010. "Trypanoside, Anti-Tuberculosis, Leishmanicidal and Cytotoxic Activities of Tetrahydrobenzothienopyrimidines." Bioorganic and Medicinal Chemistry 18 2880-2886 [Full Text (Link)]

    Aponte, J. C., A. J. Vaisberg, R. Rojas, et al. M. Sauvain, W. H. Lewis, G. Lamas, C. Sarasara, R. H. Gilman, and G. B. Hammond. 2009. "A Multipronged Approach to the Study of Peruvian Ethnomedicinal Plants: A Legacy of the ICBG-Peru Project." Journal of Natural Products 72 524-526 [Full Text (Link)]

    Aponte, J. C., G. B. Hammond, and B. Xu. 2009. "TBAF-Mediated Aldol Reaction of b-Allenoates: Regio- and Stereoselective Synthesis of (2E, 4E)-4-Carbinol Alkadienoates." Journal of Organic Chemistry 74 4623-4625 [Full Text (Link)]

    Aponte, J. C., A. J. Vaisberg, R. Rojas, et al. L. Caviedes, W. L. Lewis, G. Lamas, C. Sarasara, and R. H. Gilman. 2008. "Isolation of Cytotoxic Metabolites from Targeted Peruvian Amazonian Medicinal Plants." Journal of Natural Products 71 102-105 [Full Text (Link)]

    Aponte, J. C., Y. Estevez, R. H. Gilman, et al. W. H. Lewis, R. Rojas, M. Sauvain, A. J. Vaisberg, and G. B. Hammond. 2008. "Antiinfective and Cytotoxic Compounds Present in Blepharodon nitidum (Asclepiadaceae)." Planta Medica 74 407-410 [Full Text (Link)]

    Aponte, J. C., M. Verastegui, E. Malaga, et al. M. Zimic, M. Quiliano, A. J. Vaisberg, R. H. Gilman, and G. B. Hammond. 2008. "Synthesis, Cytotoxicity, and Anti-Trypanosoma cruzi Activity of New Chalcones." Journal of Medicinal Chemistry 51 6230-6234 [Full Text (Link)]

    Rojas, R., L. Caviedes, J. C. Aponte, et al. A. J. Vaisberg, W. H. Lewis, G. Lamas, C. Sarasara, R. H. Gilman, and G. B. Hammond. 2006. "Aegicerin, the First Oleanane Triterpene with Wide-Ranging Antimycobacterial Activity, Isolated from Clavija procera." Journal of Natural Products 69 845-846 [Full Text (Link)]

                                                                                                                                                                                            
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